We are so proud of our Research Grant awardees who selflessly dedicate their time to carry out medical research to benefit radiologic care for patients. These testimonials from past grant recipients capture the value and impact that this award provides.
The CRF has financed the following research studies since 2011:
Learning Styles in Diagnostic Radiology: Informing Curriculum Changes & Mentorship
Investigated by Dr. Linda Probyn in collaboration with Drs. Karen Finlay and Nancy Fenton
Validation of Dual Energy Cardiac CT Perfusion Imaging in an Animal Model: Correlation with Coronary Flow Reserve & Fractional Flow Reserve
Investigated by Dr. John Mayo
- Paper Development of a Porcine Model of Coronary Stenosis Using Fully Percutaneous Techniques Suitable For Performing Cardiac Computed Tomography, CT-Perfusion Imaging and Fractional Flow Reserve published in the Heart and Lung journal in July 2018
Neuroradiological, Clinical and Genetic Characterization of New Forms of Hereditary Leukoencephalopathies
Investigated by Dr. Donatella Tampieri in collaboration with Drs. Bruce Pike, Bernard Brais, Maria del Pilar Cortes and Roberta La Piana
- Paper Identification and functional characterization of a novel MTFMT mutation associated with selective vulnerability of the visual pathway and a mild neurological phenotype published in the Neurogenetics journal in April 2017
- Paper 3T MRI study discloses high clinical and MRI intrafamilial variability in CADASIL due to a novel NOTCH3 mutation published in the Clinical Neurosciences journal in Dec. 2018
- Paper Long-standing psychiatric features as the only clinical presentation in a patient with Vanishing White Matter disease published in the Neuropsychiatry and Clinical Neurosciences journal in May 2019
- Paper Adult hereditary white matter diseases with psychiatric presentation: clinical pointers and MRI algorithm to guide the diagnostic process published in the Neuropsychiatry and Clinical Neurosciences journal in May 2021
- Oral Presentation Overlapping phenotypes between MS and genetic leukoencephalopathies: a systematic MR analysis. ASNR meeting. Long Beach, California. April 22-26, 2017
- Oral Presentation Unilateral leukoencephalopathy is frequently associated with Parry-Romberg Syndrome and linear scleroderma en coup de sabre. ASNR meeting. Long Beach, California. April 22-26, 2017
- Oral Presentation Overlapping phenotypes between MS and genetic leukoencephalopathies: Lessons from our collaborative ‘White Matter Rounds. MS Xchange Conference. CRCHUM, University of Montreal, Quebec. Nov. 3, 2017
- Oral Presentation Genetic leukoencephalopathies and their overlap with inflammatory demyelinating disorders: the challenge of identifying new entities. MS Xchange Conference. CRCHUM, University of Montreal, Quebec. Nov. 16, 2018.
- Oral Presentation Adult genetic leukoencephalopathies: the challenge of identifying new entities. IRCCS C. Mondino Foundation Neurological Institute, Pavia, Italy. Jan. 9, 2019.
- Oral Presentation Inherited white matter diseases in adult patients. Italian Research Day in the World, Italian Cultural Institute, Montreal, Quebec. April 15, 2019
- Oral Presentation Adult genetic leukoencephalopathies: the challenge of identifying new entities. United Leukodystrophy Foundation Scientific Symposium and Family Conference. Itasca, Illinois. June 27-29, 2019
- Oral Presentation Hereditary white matter diseases: the usefulness of 3T MRI. MRI in the Thousand Islands. 1st Annual MRI Anatomy and Pathology Course. Kingston, Ontario. Oct. 4-5, 2019
- Oral Presentation Overlap between genetic and acquired white matter diseases: lessons from the White Matter Rounds network. Neurology Grand Round, Children’s Hospital of Eastern Ontario (CHEO), Ottawa, Ontario. Nov. 22, 2019
- Oral Presentation Genetic white matter disorders: the challenge of identifying new entities. Brain Imaging Center Scientific Retreat. Usine C, Montreal, Quebec. Dec. 10, 2019.
- Oral Presentation Genetic MS mimickers. 2020 MS Xchange Conference. University of Montreal, Quebec. Nov. 13, 2020
A Double Blind, Randomized Controlled Trial Examining the Efficacy of the Use of Tissue Plasminogen Activator (tPA) in Intra-abdominal Collections in Children – a Prospective Study
Investigated by Dr. Bairbre Connolly
- Paper Use of Tissue Plasminogen Activator in Abdominal Abscesses in Children – A Single-Center Randomized Control Trial published in the CAR journal in April 2020
A Day in the Life of MR in Canada – Profiling MR Appropriateness and Utilization in Canada
Investigated by Drs. Paul Babyn and Sonia Vanderby in collaboration with Dr. Martin Reed, Dr. Juan Nicolás Peña Sánchez and Neil Kalra
- Paper Finding the Truth in Medical Imaging: Painting the Picture of Appropriateness for Magnetic Resonance Imaging in Canada published in the CAR journal in Nov. 2015
- Paper Variations in Magnetic Resonance Imaging Provision and Processes Among Canadian Academic Centres published in the CAR journal in Feb. 2017
- Paper A Day in the life of MRI: The variety and appropriateness of exams being performed in Canada published in the CAR journal in May 2018
- Educational Exhibit Understanding Magnetic Resonance Imaging Appropriateness in Canada: A Literature Review on Current Practices, Utilization, and Appropriateness. Canadian Association of Radiologists 77th Annual Scientific Meeting. Montreal, Quebec. April 24-27, 2014.
- Poster Presentation A Picture of Magnetic Resonance Imaging Appropriateness in Canada: A Literature Review. Canadian Association for Health Services and Policy Research (CAHSPR) Conference. Toronto, Ontario. May 14, 2014.
- Oral Presentation Magnetic Resonance Imaging Appropriateness in Canada: A Current Research Summary on Practices, Utilization, and Appropriateness. Quality in Medical Imaging Symposium – A Focus on Appropriateness. University of Saskatchewan. Saskatoon, Saskatchewan. October 16, 2014.
- Oral Presentation Painting the Picture of Appropriateness for Magnetic Resonance Imaging in Canada. Quality Improvement and Patient Safety in Medical Education Symposium. University of Saskatchewan. Saskatoon, Saskatchewan. November 23, 2015.
- Poster Presentation Quality Improvement and Appropriateness in Residency Education: A Novel Example. International Conference on Residency Education, Niagara Falls, Ontario. October 1, 2016
MRI Appearance of Focal Liver Lesions with Gadofosveset Trisodium
Investigated by Dr. Laurent Milot
- Paper Appearance of Focal Liver Lesions Using Contrast-Enhanced Magnetic Resonance Imaging Using Gadofosveset Trisodium, an Intravascular (Blood-Pool) Contrast Agent: A Pictorial Essay published in the CAR journal in Aug. 2016
24 hour Infarct Volume on Non-contrast CT as a Predictor of Functional Outcome at 90 days
Investigated by Dr. Helin Bai
- Poster Presentation 24 hour Infarct Volume on Non-contrast CT as a Predictor of Functional Outcome at 90 days. Bridging Discovery Research with Therapies Conference, Banff, Alberta. Aug. 27-31, 2017.
Low Cost Nanoparticle Platform for Diagnosis and Treatment of Colorectal Liver Metastases
Investigated by Dr. David Liu in collaboration with Dr. Alda Tam and Marites Melancon
- Paper A novel irinotecan-lipiodol nanoemulsion for intravascular administration: pharmacokinetics and biodistribution in the normal and tumor bearing rat liver published in the Drug Delivery journal in Dec. 2020
- Oral Presentation Creation of a nanoparticle drug delivery platform with Lipiodol, doxorubicin and irinotecan. Method and performance characteristics. Global Embolization Symposium and Technologies conference. New York, New Jersey. May 5, 2016
Can we Improve Detection of Peritoneal Metastatic Disease? The Use of Virtual Monochromatic Reconstruction on Dual Energy CT Scans
Investigated by Dr. Kathryn Darras
- Paper Virtual monoenergetic reconstruction of contrast-enhanced CT scans of the abdomen and pelvis at 40 keV improves the detection of peritoneal metastatic deposits published in the Abdominal Radiology journal in Feb. 2019
- Oral Presentation Virtual Monochromatic Reconstruction of Contrast-enhanced Dual-energy CT at 40 Kev Maximizes the Conspicuity of Peritoneal Metastases Compared with Polychromatic CT. 79th Annual Scientific Meeting, Canadian Association of Radiologists, Montreal. April 2016, and Department of Radiology Research Day, Faculty of Medicine, University of British Columbia. June 2016, and 101st Annual Scientific Meeting, RSNA, Chicago, Illinois. Nov-Dec 2016
Utilization of Pre-Operative Imaging for Colon Cancer: a Population-based Study
Investigated by Dr. Matthew McInnes, Dr. Sulaiman Nanji, Dr. William Mackillop, Dr. Yingwei Peng, Shelly Wei, Dr. D Blair Macdonald, Dr. Nicola Schieda and Dr. Christopher Booth
- Paper Utilization of pre-operative imaging for colon cancer: A population-based study published in the Journal of Surgical Oncology in Nov. 2016
- Scientific Exhibit Utilization of pre-operative imaging for colon cancer: a population-based study. 80th Annual Scientific Meeting, Canadian Association of Radiologists, Montreal. April 2017
Adaptive Personalized Predictive Risk Model for Medical Imaging Radiation Exposure
Investigated by Dr. David Koff
- Paper Blockchain Enabled Privacy Audit Logs published in the International Semantic Web Conference in Oct. 2017
- Paper Digitized Trust in Human-in-the-Loop Health Research published in the 16th Annual Conference on Privacy, Security and Trust (PST) in 2018
- Paper Timestamp-based Integrity Proofs for Linked Data published in the International Workshop on Semantic Big Data – SIGMOD in June 2018
- Paper Machine Learning and Mobile Health Monitoring Platforms: A Case Study on Research and Implementation Challenges published in the Journal of Health Informatics Research in June 2018
- Paper An Environmental Scan of the National and Provincial Diagnostic Reference Levels in Canada for Common Adult Computed Tomography Scans published in the CAR Journal in May 2019
- Paper From Group-Level Statistics to Single-Subject Prediction: Machine Learning Detection of Concussion in Retired Athletes published in IEEE Transactions on Neural Systems and Rehabilitation Engineering in July 2019
- Paper Using Medical Imaging Effective Dose in Deep Learning Models: Estimation and Evaluation published in IEEE Transactions on Radiation and Plasma Medical Sciences in March 2021
- Oral Presentation What is the risk posed by future medical scans? SOSCIP Impact Conference. MaRS Centre, Toronto, Ontario. May 9, 2017
- Oral Presentation. Metric Engineering Technology Research and Innovation Conference. Sept. 2017
- Oral Presentation Blockchain Enabled Privacy Audit Logs. International Semantic Web Conference, Vienna Austria. Oct. 2017, and The First Workshop on Blockchain & eHealth: Towards Provable Privacy & Security on Data Intensive Health Research, International Conference on Computer Science and Software Engineering, IBM CASCON, Markham, Ontario. Nov. 2017
- Poster Presentation A Blockchain Architecture for Active Machine Learning Algorithms. McMaster AI Workshop, Hamilton, Ontario. 2017, and McMaster Biomedical Engineering Symposium, Hamilton, Ontario. Jan. 2018
- Talk. McMaster eHealth graduate program Seminar Series, Hamilton, Ontario. Jan. 2018
- Oral Presentation Computer Aided Detection: The Future of Lung Cancer Screening. Canadian Association of Radiologists Annual Scientific Meeting, Montreal Quebec. April 2018
- Talk. Hamilton General Hospital, Division of Emergency Medicine Regional Rounds Series, Hamilton, Ontario. May 2018.
- Poster Presentation An Architecture for Continuous Active Learning Algorithms. Vector Research Symposium. Toronto, Ontario. Feb. 2019, and McMaster Biomedical Engineering Symposium, Hamilton, Ontario. April 2019
Teaching Safe Imaging: Development and Evaluation of an Online Imaging Appropriateness Course for Canadian Medical Students
Investigated by Dr. Kathryn Darras, Dr. Savvas Nicolaou and Dr. Bruce B Forster
Designing an introductory to image guided invasive procedures workshop
Investigated by Dr. Emeka Nzekwu, Dr. Vamshi Kotha, Dr. Morgan Willson and Dr. Alice Wang
- Findings only presented at Grand Rounds hosted at the University of Calgary due to consent limitations for the subjects
Quantitative BOLD MRI as a non-invasive tool to unmask the role of glioma stem cells in patients with glioblastoma
Investigated by Dr. Pejman Jabehdar Maralani
Machine Learning for Liver Imaging: Automating LI-RADS Categorization
Investigated by Christian van der Pol, Dr. David Koff, Dr. Kiret Dhindsa, Dr. Thomas Doyle, Dr. Sandra Monteiro, Dr. Pablo Serrano and Dr. Brandon Meyers
- Paper Imaging Reporting and Data System (LI-RADS) Version 2018: Impact of and Reduction in Ancillary Features published in the American Journal of Roentgenology in April 2021
- Poster Presentation Machine Learning Applied to Liver Imaging: Automating Liver Imaging Reporting and Data System (LI-RADS) Categorization. Radiology Society of North America Annual Meeting, Chicago, Illinois. Dec. 2020
Effect of polyphenol supplementation on hepatic steatosis, non-invasive vascular elastography and intima media thickness in obese adolescents
Investigated by Dr. Ramy El Jalbout
BRAIN-REST: Brain MRI result forecast model
Investigated by Dr. Matthias Wagner
Using AI to determine prevalence of pre- or asymptomatic COVID-19 in patients undergoing chest CT for a non COVID indication within Eastern Ontario – a collaborative multicenter observational study
Investigated by Dr. Robert Lim
Using Virtual Reality as a Remote Educational Tool During the COVID-19 Pandemic
Investigated by Dr. Yuhao Wu
Quantitative MR to distinguish genetic mimickers from multiple sclerosis
Investigated by Dr. Roberta La Piana
Developing process-based interventional radiology quality indicators: a novel approach to assessing the quality of care of patients undergoing interventional radiology procedures
Investigated by Dr. Helena Bentley
Effect of the Covid-19 pandemic on emergency departments presentations of appendicitis or diverticulitis across Eastern Newfoundland
Investigated by Dr. Brandon Collins
- Paper Effect of the COVID‑19 pandemic on emergency department utilization of computed tomography scans of appendicitis and diverticulitis published online in the Emergency Radiology journal in March 2023.
- Oral presentation Effect of the COVID-19 pandemic on emergency department utilization of computed tomography scans of appendicitis and diverticulitis. American Roentgen Society (ARRS) 2023 conference.
Myocardial Injury and Outcomes Following COVID-19 Vaccination (MYOVAX Study)
Investigated by Dr. Kate Hanneman
The impact of the COVID-19 pandemic on breast cancer method of detection and
stage at diagnosis at The Ottawa Hospital
Investigated by Dr. Mary Beth Bissell
Neurite Orientation Dispersion and Density Imaging for Microscopic Tissue Evaluation in Aneurysmal Subarachnoid Hemorrhage
Investigated by Dr. Jesse Klostranec
CT Chest Findings in Marijuana smokers compared to tobacco and non- smokers: A prospective cohort study
Investigated by Dr. Giselle Revah
- Oral presentation Is Smoking Marijuana Safe? The Effects of Smoking Cannabis on the Chest. RSNA 2023 annual meeting.
